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CAS RN 257933-82-7

CH3ONNHNFClNHONH3CCH3(E)

CAS RN 257933-82-7

IUPAC Name: (2E)-N-{4-[(3-chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxyquinolin-6-yl}-4-(dimethylamino)but-2-enamide
Synonyms: pelitinib
Molecular Weight (g/mol): 467.93
Molecular Formula: C24H23ClFN5O2
InChi Key: WVUNYSQLFKLYNI-AATRIKPKSA-N
SMILES: CCOC1=C(NC(=O)\C=C\CN(C)C)C=C2C(NC3=CC=C(F)C(Cl)=C3)=C(C=NC2=C1)C#N
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1

Pelitinib, TRC

CAS: 257933-82-7 Molecular Formula: C24 H23 Cl F N5 O2 Molecular Weight (g/mol): 467.92 IUPAC Name: (E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide SMILES: CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C

CAS 257933-82-7
Molecular Weight (g/mol) 467.92
SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)\C=C\CN(C)C
IUPAC Name (E)-N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxyquinolin-6-yl]-4-(dimethylamino)but-2-enamide
Molecular Formula C24 H23 Cl F N5 O2
2

Pelitinib, MedChemExpress

MedChemExpress Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC50 of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282, 800, and 1255 nM, respectively.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 467.92
Color Off-White
Physical Form Solid
Chemical Name or Material Pelitinib
Grade Research
SMILES N#CC1=C(C2=CC(NC(/C=C/CN(C)C)=O)=C(OCC)C=C2N=C1)NC3=CC(Cl)=C(C=C3)F
For Use With (Application) Cancer-Kinase/protease
Percent Purity 96.96%
CAS 257933-82-7
Solubility Information DMSO : 25 mg/mL (53.43 mM; Need ultrasonic)
Health Hazard 1 H301
Synonym EKB-569 WAY-EKB 569
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C24H23ClFN5O2
Formula Weight 467.92
3

Tocris Bioscience™ Pelitinib
GREENER_CHOICE

Potent and irreversible EGFR inhibitor (IC50 = 20-80 nM); orally bioavailable

CAS 257933-82-7
Purity 97%
Chemical Name or Material (2E)-N-[4-[(3-Chloro-4-fluorophenyl)amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Recommended Storage Store at -20°C
Synonym EKB-569
Molecular Formula C24H23ClFN5O2
Formula Weight 467.92