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Pelitinib, MedChemExpress

Product Code. 16498038
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16498038 10 mg 10mg
16493957 50 mg 50mg
16473746 25 mg 25mg
16447816 100 mg 100mg
16430508 5 mg 5mg
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Product Code. 16498038 Supplier Medchem Express Supplier No. HY32718

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Description

MedChemExpress Pelitinib (EKB-569;WAY-EKB 569) is an irreversible inhibitor of EGFR with an IC50 of 38.5 nM; also slightly inhibits Src, MEK/ERK and ErbB2 with IC50s of 282, 800, and 1255 nM, respectively.

Pelitinib (EKB-569

Specifications

Chemical Name or Material Pelitinib
CAS 257933-82-7
Color Off-White
Purity Grade Notes Research
Molecular Formula C24H23ClFN5O2
Quantity 10 mg
Synonym EKB-569 WAY-EKB 569
Solubility Information DMSO : 25 mg/mL (53.43 mM; Need ultrasonic)
SMILES N#CC1=C(C2=CC(NC(/C=C/CN(C)C)=O)=C(OCC)C=C2N=C1)NC3=CC(Cl)=C(C=C3)F
Molecular Weight (g/mol) 467.92
Formula Weight 467.92
Percent Purity 96.96%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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