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R&D Systems™ Mca-SEVNLDAEFRK(Dnp)RR-NH2 Fluorogenic Peptide Substrate
Description
- Contains a highly fluorescent 7-methoxycoumarin group that is efficiently quenched by resonance energy transfer to the 2, 4-dinitrophenyl group
- It can be used to measure the activities of peptidases that are capable of cleaving an amide bond between the fluorescent group and the quencher group, causing an increase in fluorescence
- Purity 93.8% by HPLC
- Contains the Swedish mutation of the amyloid precursor protein (APP) beta-secretase cleavage site
- A K-R-R sequence is added for easy solubilization
Specifications
Specifications
| Form | Liquid |
| For Use With (Application) | Bioactivity |
| Quantity | 1 mg |
| Format | Supplied as a stock solution in dimethyl sulfoxide (DMSO) (100μL) at a concentration of 10.0mg/mL or 4.1 mM.. |
| Molecular Weight (g/mol) | Predicted MW: 2001 Da |
| Product Type | Source: Synthetic |
| Storage Requirements | Samples are stable for up to twelve months from date of receipt at -20° C to -70° C. The substrate can be aliquoted and stored -20° C to -70° C in a manual defrost freezer for six months. Avoid repeated freeze-thaw cycles. Protect from exposure to direct light |
Product Title
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