CAS RN 4727-31-5
CAS RN 4727-31-5
Thermo Scientific Chemicals Kartogenin
CAS: 4727-31-5 Molecular Formula: C20H15NO3 Molecular Weight (g/mol): 317.34 InChI Key: SLUINPGXGFUMLL-UHFFFAOYSA-N IUPAC Name: 2-({[1,1'-biphenyl]-4-yl}carbamoyl)benzoic acid SMILES: OC(=O)C1=CC=CC=C1C(=O)NC1=CC=C(C=C1)C1=CC=CC=C1
Tocris Bioscience™ Kartogenin
CAS: 4727-31-5 Molecular Formula: C20H15NO3
Kartogenin, TRC
CAS: 4727-31-5 Molecular Formula: C20 H15 N O3 Molecular Weight (g/mol): 317.34 Synonym: 2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic Acid,2-[(Biphenyl-4-yl)carbamoyl]benzoic Acid,4'-Phenylphthalanilic Acid,KGN; IUPAC Name: 2-[(4-phenylphenyl)carbamoyl]benzoic acid SMILES: OC(=O)c1ccccc1C(=O)Nc2ccc(cc2)c3ccccc3
Kartogenin, MedChemExpress
MedChemExpress Kartogenin (KGN) is an inducer of differentiation of human mesenchymal stem cells into chondrocytes, with an EC50 of 100 nM. Kartogenin binds filamin A, disrupts its interaction with the transcription factor core-binding factor β subunit (CBFβ), and induces chondrogenesis by regulating the CBFβ-RUNX1 transcriptional program. Kartogenin can be used for the research of osteoarthritis (OA).