CAS RN 415903-37-6

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CJ-023423, TRC

CAS: 415903-37-6 Molecular Formula: C26H29N5O3S Molecular Weight (g/mol): 491.61 IUPAC Name: 1-[2-[4-(2-ethyl-4,6-dimethylimidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]-3-(4-methylphenyl)sulfonylurea SMILES: CCc1nc2c(C)nc(C)cc2n1c3ccc(CCNC(=O)NS(=O)(=O)c4ccc(C)cc4)cc3

Pricing and Availability
Specifications

CAS	415903-37-6
Molecular Weight (g/mol)	491.61
SMILES	CCc1nc2c(C)nc(C)cc2n1c3ccc(CCNC(=O)NS(=O)(=O)c4ccc(C)cc4)cc3
IUPAC Name	1-[2-[4-(2-ethyl-4,6-dimethylimidazo[4,5-c]pyridin-1-yl)phenyl]ethyl]-3-(4-methylphenyl)sulfonylurea
Molecular Formula	C26H29N5O3S

Grapiprant, MedChemExpress

MedChemExpress Grapiprant (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). Grapiprant displaces [3H]-PGE2 (1 nM) binding to dog recombinant EP4 receptor with IC50 value of 35 nM and Ki value of 24 nM. Grapiprant has the potential for osteoarthritic pain and inflammation treatment[3] .

Pricing and Availability
Specifications

Molecular Weight (g/mol)	491.61
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Grapiprant
Grade	Research
SMILES	O=S(C1=CC=C(C)C=C1)(NC(NCCC2=CC=C(N3C(CC)=NC4=C3C=C(C)N=C4C)C=C2)=O)=O
For Use With (Application)	Metabolism-protein/nucleotide metabolism
Percent Purity	99.02%
CAS	415903-37-6
Solubility Information	DMSO : ≥ 50 mg/mL (101.71 mM)
Synonym	CJ-023423 RQ-00000007 AAT-007
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₆H₂₉N₅O₃S
Formula Weight	491.61

CAS RN 415903-37-6

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