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CAS RN 184475-35-2

CH3ONNHNFClONO

CAS RN 184475-35-2

IUPAC Name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(morpholin-4-yl)propoxy]quinazolin-4-amine
Synonyms: gefitinib tarceva gefitinib preparation iressa C22H24ClFN4O3 gefitinib (substance) gefitinib (product) irressat
Molecular Weight (g/mol): 446.91
Molecular Formula: C22H24ClFN4O3
InChi Key: XGALLCVXEZPNRQ-UHFFFAOYSA-N
SMILES: COC1=C(OCCCN2CCOCC2)C=C2C(NC3=CC=C(F)C(Cl)=C3)=NC=NC2=C1
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Tocris Bioscience™ Iressa
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CAS: 184475-35-2 Molecular Formula: C22H24ClFN4O3

CAS 184475-35-2
Molecular Formula C22H24ClFN4O3
2

Gefitinib, Mikromol™

Discover Mikromol - your trusted source for high-quality pharmaceutical reference standards. Supporting accurate, compliant analysis with ISO 17034-accredited materials designed for confidence in every result.

3

Gefitinib, TRC

CAS: 184475-35-2 Molecular Formula: C22 H24 Cl F N4 O3 Molecular Weight (g/mol): 446.9 IUPAC Name: N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine SMILES: COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4

CAS 184475-35-2
Molecular Weight (g/mol) 446.9
SMILES COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN4CCOCC4
IUPAC Name N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Molecular Formula C22 H24 Cl F N4 O3
4

Gefitinib, MedChemExpress

MedChemExpress Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer .

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 446.9
Color White
Physical Form Powder
Chemical Name or Material Gefitinib
Grade Research
SMILES ClC1=C(C=CC(NC2=NC=NC3=C2C=C(C(OC)=C3)OCCCN4CCOCC4)=C1)F
For Use With (Application) Cancer-Kinase/protease
Percent Purity 95.0%
CAS 184475-35-2
Solubility Information DMSO : 125 mg/mL (279.70 mM; Need ultrasonic)
Health Hazard 1 H302∣H315∣H319∣H332∣H335
Synonym ZD1839
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C22H24ClFN4O3
Formula Weight 446.9
5

STEMCELL Technologies Gefitinib

Tyrosine kinase inhibitor; Inhibits EGFR

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