CAS RN 1628805-46-8

IUPAC Name: —

Synonyms: —

Molecular Weight (g/mol): —

Molecular Formula: —

InChi Key: —

SMILES: —

1 – 1 of 1 results

IDH-305, MedChemExpress

MedChemExpress IDH-305 is an orally available, mutant-selective and brain-penetrant IDH1 inhibitor that targets IDH1 (R132) mutation. IDH-305 exhibits greater than 200 fold selectivity for mutant IDH1 isoforms vs. WT (IC50= 27 nM (IDH1R132H), 28 nM (IDH1R132C), 6.14 μM (IDH1WT)).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	490.45
Color	Off-White
Physical Form	Solid
Chemical Name or Material	IDH-305
Grade	Research
SMILES	O=C1OC[C@H]([C@@H](F)C)N1C2=NC(N[C@H](C3=CC(C)=C(C4=CC(C(F)(F)F)=NC=C4)C=N3)C)=NC=C2
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.0%
CAS	1628805-46-8
Solubility Information	DMSO : ≥ 150 mg/mL (305.84 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₃H₂₂F₄N₆O₂
Formula Weight	490.45

CAS RN 1628805-46-8

CAS RN 1628805-46-8

Filtered Search Results

Narrow Results