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CAS RN 1032350-13-2

CAS RN 1032350-13-2

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Tocris Bioscience™ MK 2206 dihydrochloride
GREENER_CHOICE

Potent and selective allosteric Akt1, Akt2 and Akt3 inhibitor

Target Akt (Protein Kinase B) Inhibitors
CAS 1032350-13-2
Purity 0.98
Chemical Name or Material 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride
Recommended Storage Store at -20°C
Molecular Formula C25H21N5O.2HCl
2

MK-2206 Dihydrochloride, TRC

CAS: 1032350-13-2 Molecular Formula: C25 H21 N5 O . 2 Cl H Molecular Weight (g/mol): 480.39 Synonym: MK 2206 dihydrochloride IUPAC Name: 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride SMILES: Cl.Cl.NC1(CCC1)c2ccc(cc2)c3nc4C=CN5C(=O)NN=C5c4cc3c6ccccc6

CAS 1032350-13-2
Molecular Weight (g/mol) 480.39
SMILES Cl.Cl.NC1(CCC1)c2ccc(cc2)c3nc4C=CN5C(=O)NN=C5c4cc3c6ccccc6
Synonym MK 2206 dihydrochloride
IUPAC Name 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-2H-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-one;dihydrochloride
Molecular Formula C25 H21 N5 O . 2 Cl H
3

MK-2206 dihydrochloride, MedChemExpress

MedChemExpress MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active allosteric AKT inhibitor with IC50s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively. MK-2206 dihydrochloride induces autophagy.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 480.39
Color Green Yellow
Physical Form Solid
Chemical Name or Material MK-2206 dihydrochloride
Grade Research
SMILES O=C1N2C(C3=CC(C4=CC=CC=C4)=C(N=C3C=C2)C5=CC=C(C6(N)CCC6)C=C5)=NN1.Cl.Cl
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.89%
CAS 1032350-13-2
Solubility Information DMSO : 16.67 mg/mL (34.70 mM; ultrasonic and warming and heat to 70°C) ∣H2O : 3.57 mg/mL (7.43 mM; ultrasonic and warming and heat to 60°C)
Synonym MK-2206 (2HCl)
Purity Grade Notes Research
Recommended Storage 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula C25H23Cl2N5O
Formula Weight 480.39