Imidazoles

Aromatic organic heterocyclic compounds that consist of a diazole with non-adjacent nitrogen atoms with the formula: C3N2H4.

1 – 15 of 25 results

NAI-N3, MedChemExpress

MedChemExpress NAI-N3 is a RNA acylation reagent that enables RNA purification. NAI-N3 is a dual-function SHAPE (selective 2-hydroxyl acylation and profiling experiment) probe (RNA structure probe and enrichment).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	228.21
Color	White
Physical Form	Solid
Chemical Name or Material	NAI-N3
Grade	Research
SMILES	O=C(C1=CC=CN=C1CN=[N+]=[N-])N2C=CN=C2
Percent Purity	95.0%
CAS	1612756-29-2
Solubility Information	DMSO : 250 mg/mL (1095.48 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₁₀H₈N₆O
Formula Weight	228.21

Decoyinine, MedChemExpress

MedChemExpress Decoyinine is a selective inhibitor of GMP synthetase (GMPS).

Pricing and Availability
Specifications

Molecular Weight (g/mol)	279.25
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Decoyinine
Grade	Research
SMILES	C=C(O1)[C@@H](O)[C@@H](O)[C@]1(CO)N2C=NC3=C(N)N=CN=C32
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.0%
CAS	2004-04-8
Solubility Information	DMSO : 50 mg/mL (179.05 mM; ultrasonic and warming and heat to 60°C)
Synonym	Angustmycin A
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₁H₁₃N₅O₄
Formula Weight	279.25

Nilotinib, MedChemExpress

MedChemExpress Nilotinib is an orally available Bcr-Abl tyrosine kinase inhibitor with antineoplastic activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	529.52
Color	Yellow
Physical Form	Solid
Chemical Name or Material	Nilotinib
Grade	Research
SMILES	O=C(NC1=CC(C(F)(F)F)=CC(N2C=NC(C)=C2)=C1)C3=CC=C(C)C(NC4=NC=CC(C5=CC=CN=C5)=N4)=C3
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	99.6%
CAS	641571-10-0
Solubility Information	DMSO : < 1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble or slightly soluble)
Synonym	AMN107
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₂₂F₃N₇O
Formula Weight	529.52

Bilastine, MedChemExpress

MedChemExpress Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	463.61
Color	White
Physical Form	Solid
Chemical Name or Material	Bilastine
Grade	Research
SMILES	CC(C)(C1=CC=C(CCN2CCC(C3=NC4=CC=CC=C4N3CCOCC)CC2)C=C1)C(O)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.32%
CAS	202189-78-4
Solubility Information	DMSO : 10 mg/mL (21.57 mM; ultrasonic and warming and heat to 60°C)
Health Hazard 1	H302
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₈H₃₇N₃O₃
Formula Weight	463.61

AG14361, MedChemExpress

MedChemExpress AG14361 is a potent PARP-1 inhibitor, with a Ki of IC50s are 29 nM and 14 nM, respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	320.39
Color	Off-White
Physical Form	Solid
Chemical Name or Material	AG14361
Grade	Research
SMILES	O=C1NCCN2C3=C1C=CC=C3N=C2C4=CC=C(C=C4)CN(C)C
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.05%
CAS	328543-09-5
Solubility Information	DMSO : 50 mg/mL (156.06 mM; ultrasonic and warming and heat to 80°C)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₉H₂₀N₄O
Formula Weight	320.39

STO-609, MedChemExpress

MedChemExpress STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ∼0.02 g/ml.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	314.29
Color	Yellow
Physical Form	Powder
Chemical Name or Material	STO-609
Grade	Research
SMILES	O=C(C1=C2C3=C(C4=NC5=CC=CC=C5N4C(C3=CC=C2)=O)C=C1)O
For Use With (Application)	Metabolism-sugar/lipid metabolism
Percent Purity	98.0%
CAS	52029-86-4
Solubility Information	DMSO : 6.25 mg/mL (19.89 mM; ultrasonic and warming and heat to 80°C) ∣DMF : 5.56 mg/mL (17.69 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (insoluble)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₁₉H₁₀N₂O₃
Formula Weight	314.29

Cordycepin, MedChemExpress

MedChemExpress Cordycepin (3'-Deoxyadenosine) is a nucleoside derivative and inhibits IL-1β-induced MMP-1 and MMP-3 expression in rheumatoid arthritis synovial fibroblasts (RASFs) in a dose-dependent manner. Cordycepin kills Mycobacterium tuberculosis through hijacking the bacterial adenosine kinase.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	251.24
Color	White
Physical Form	Solid
Chemical Name or Material	Cordycepin
Grade	Research
SMILES	OC[C@@H]1C[C@H]([C@H](N2C=NC3=C2N=CN=C3N)O1)O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.64%
CAS	73-03-0
Solubility Information	DMSO : 50 mg/mL (199.01 mM; Need ultrasonic) ∣H2O : 2 mg/mL (7.96 mM; ultrasonic and warming and heat to 60°C)
Synonym	3'-Deoxyadenosine
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₀H₁₃N₅O₃
Formula Weight	251.24

Deltarasin, MedChemExpress

MedChemExpress Deltarasin is an inhibitor of KRAS-PDEδ interaction with Kd of 38 nM for binding to purified PDEδ.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	603.75
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	Deltarasin
Grade	Research
SMILES	C1(C2=CC=C(OC[C@@H](N3C4=CC=CC=C4N=C3C5=CC=CC=C5)C6CCNCC6)C=C2)=NC7=CC=CC=C7N1CC8=CC=CC=C8
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	1440898-61-2
Solubility Information	DMSO : ≥ 42 mg/mL (69.57 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₄₀H₃₇N₅O
Formula Weight	603.75

Dabigatran (ethyl ester), MedChemExpress

MedChemExpress Dabigatran ethyl ester is an emerging oral anticoagulant which is a direct inhibitor of thrombin activity.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	499.56
Color	White
Physical Form	Solid
Chemical Name or Material	Dabigatran (ethyl ester)
Grade	Research
SMILES	O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(N)=N)C=C4)=C2
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.0%
CAS	429658-95-7
Solubility Information	H2O : 1 mg/mL (2.00 mM; ultrasonic and warming and heat to 80°C) ∣DMSO : 1 mg/mL (2.00 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₇H₂₉N₇O₃
Formula Weight	499.56

7-Methylguanosine, MedChemExpress

MedChemExpress 7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor with IC50 value of 87.8 ± 7.5 μM.

Pricing and Availability

N-[(4-Aminophenyl)methyl]adenosine, MedChemExpress

MedChemExpress N-[(4-Aminophenyl)methyl]adenosine is a adenosine receptor inhibitor, with Ki of 29 nM for Rat ecto-5′-Nucleotidase.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	372.38
Color	Off-White
Physical Form	Solid
Chemical Name or Material	N-[(4-Aminophenyl)methyl]adenosine
Grade	Research
SMILES	OC[C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=CN=C3NCC4=CC=C(N)C=C4)O1)O)O
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	98.0%
CAS	95523-13-0
Solubility Information	DMSO : 10 mg/mL (26.85 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₇H₂₀N₆O₄
Formula Weight	372.38

SB-772077B dihydrochloride, MedChemExpress

MedChemExpress SB-772077B dihydrochloride is an aminofurazan-based Rho kinase (ROCK) inhibitor with IC50s of 5.6 nM and 6 nM toward ROCK1 and ROCK2, respevtively.

Pricing and Availability

Gln-AMS TFA, MedChemExpress

MedChemExpress Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor. Gln-AMS inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	588.47
Color	Off-White
Physical Form	Solid
Chemical Name or Material	Gln-AMS TFA
Grade	Research
SMILES	O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CCC(N)=O)=O)=O.OC(C(F)(F)F)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	98.73%
Solubility Information	H2O : 130 mg/mL (220.91 mM; Need ultrasonic) ∣DMSO : 50 mg/mL (84.97 mM; ultrasonic and warming and heat to 60°C)
Purity Grade Notes	Research
Recommended Storage	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	-20°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₁₇H₂₃F₃N₈O₁₀S
Formula Weight	588.47

5'-N-Ethylcarboxamidoadenosine, MedChemExpress

MedChemExpress 5'-N-Ethylcarboxamidoadenosine (NECA) is a nonselective adenosine receptor agonist.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	308.29
Color	Off-White
Physical Form	Solid
Chemical Name or Material	5'-N-Ethylcarboxamidoadenosine
Grade	Research
SMILES	O[C@H]1[C@H](N2C=NC3=C(N)N=CN=C23)O[C@H](C(NCC)=O)[C@H]1O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.34%
CAS	35920-39-9
Solubility Information	DMSO : 62.5 mg/mL (202.73 mM; Need ultrasonic) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1	H300
Synonym	NECA
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₁₂H₁₆N₆O₄
Formula Weight	308.29

Conivaptan hydrochloride, MedChemExpress

MedChemExpress Conivaptan (hydrochloride) is a non-peptide antagonist of vasopressin receptor, with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	535.04
Color	White
Physical Form	Solid
Chemical Name or Material	Conivaptan hydrochloride
Grade	Research
SMILES	O=C(C1=CC=CC=C1C2=CC=CC=C2)NC3=CC=C(C(N4CCC(N=C(C)N5)=C5C6=CC=CC=C64)=O)C=C3.Cl
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.61%
CAS	168626-94-6
Solubility Information	DMSO : ≥ 100 mg/mL (186.90 mM) ∣H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 60°C) (insoluble)
Health Hazard 1	H361
Synonym	YM 087
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
Shelf Life	4°C, sealed storage, away from moisture and light∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture and light)
Molecular Formula	C₃₂H₂₇ClN₄O₂
Formula Weight	535.04

Imidazoles

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