missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 18763979

Tocris Bioscience™ VTP 27999 trifluoroacetate
GREENER_CHOICE

Product Code. 18763979
Change view
Click to view available options
Quantity:
10 mg
Unit Size:
10mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18763979 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 18763979 Supplier Tocris Bioscience™ Supplier No. 5563/10

Please to purchase this item. Need a web account? Register with us today!

136.00 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

Highly potent and selective renin inhibitor

VTP 27999 trifluoroacetate is a highly potent and selective renin inhibitor (IC50 = 0.47 nM). Displays >1000-fold selectivity over related and unrelated off-targets. Blocks renin-stimulated ERK1/2 phosphorylation in vascular smooth muscle cells. Exhibits a different mode of action to aliskiren (Cat. No. 5491).
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material Methyl N-[2-[(R)-(3-Chlorophenyl)[(3R)-1-[[[(2S)-2-(methylamino)-3-[(3R)-tetrahydro-2H-pyran-3-yl]propyl]amino]carbonyl]-3-piperidinyl]methoxy]ethyl]carbamate trifluoroacetate
CAS 1013937-63-7
Quantity 10 mg
Target Additional Synthetic Protease Inhibitors
Molecular Formula C26H41ClN4O5.CF3CO2H
Formula Weight 639.1
Purity >97%
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.