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Tocris Bioscience™ Sazetidine A dihydrochloride
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Product Code. 18045052
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10 mg
Unit Size:
10mg
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18045052 10 mg 10mg
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Product Code. 18045052 Supplier Tocris Bioscience™ Supplier No. 2736/10

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Description

α4β2 receptor ligand; may act as an agonist or a desensitizer

Subtype-selective α4β2 nicotinic acetylcholine receptor ligand (Ki values are 0.26 and 54 nM at α4β2 and α3β4 receptors respectively). May act as a silent desensitizer or as an agonist, depending on subunit stoichiometry (EC50 = 1.1 nM for nAChR-stimulated dopamine release). Exhibits analgesic activity in vivo and significantly reduces nicotine self-administration in an experimental rat model.
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Specifications

CAS 2455450-63-0
Quantity 10 mg
Molecular Formula C15H22Cl2N2O2
Formula Weight 333.25
Purity >98%
Molecular Weight (g/mol) 333.25
Chemical Name or Material Sazetidine A dihydrochloride
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