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(S)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%

Product Code. 11323476
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Product Code. 11323476 Supplier Thermo Scientific Alfa Aesar Supplier No. L14332.MF
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CAS: 20445-33-4 | C10H8ClF3O2 | 252.617 g/mol

(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used in the preparation of natural products and pheromones. It is also employed as a derivatization enantiomeric purity reagent used for the determination of enantiomeric purity of alcohol and amines by gas chromatography.

Solubility
Slightly miscible with water.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents, strong acids and bases.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 20445-33-4
Molecular Formula C10H8ClF3O2
Molecular Weight (g/mol) 252.617
MDL Number MFCD00067105
InChI Key PAORVUMOXXAMPL-SECBINFHSA-N
Synonym s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, +-mtpa-cl, unii-472va70ul4, 2s-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride, s-+-alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride, s-+-a-methoxy-a-trifluoromethylphenylacetyl chloride, s-+-alpha-methoxy-alpha-trifluoromethylphenylacetylchloride, s-+-alpha-methoxy-alpha-trifluoromethyl phenylacetyl chloride, +-mtpa chloride, +-mosher's chloride
PubChem CID 2724611
IUPAC Name (2S)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
SMILES COC(C1=CC=CC=C1)(C(=O)Cl)C(F)(F)F

Specifications

Density 1.353
Boiling Point 213°C to 214°C
Flash Point 89°C (192°F)
Refractive Index 1.469
Quantity 50 mg
UN Number UN3265
Beilstein 3591564
Sensitivity Moisture sensitive
Merck Index 14,6280
Solubility Information Slightly miscible with water.
Optical Rotation +137° (c=6.4 in Carbon Tetrachloride)
Formula Weight 252.62
Percent Purity ≥98%
Chemical Name or Material (S)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
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