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Tocris Bioscience™ Pifithrin-α hydrobromide
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Product Code. 18065102
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18065102 10 mg 10mg
18035452 50 mg 50mg
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Product Code. 18065102 Supplier Tocris Bioscience™ Supplier No. 1267/10

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Description

p53 inhibitor. Also aryl hydrocarbon receptor agonist

Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of cancer therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM). Cyclic analog available (Cat. No. 3843).
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 63208-82-2
Molecular Formula C16H19BrN2OS

Specifications

Quantity 10 mg
Formula Weight 367.3
Purity >98%
Molecular Weight (g/mol) 367.305
Chemical Name or Material Pifithrin-α hydrobromide
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