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Tocris Bioscience™ LY 487379 hydrochloride
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Product Code. 18094432
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18034252 10 mg 10mg
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Product Code. 18094432 Supplier Tocris Bioscience™ Supplier No. 3283/50

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Selective positive allosteric modulator of mGlu2 receptors

Positive allosteric modulator selective for mGlu2 receptors. Potentiates glutamate-stimulated [35S]GTPγS binding (EC50 values are 1.7 and > 10 μM for mGlu2 and mGlu3 receptors respectively). Devoid of any activity at mGlu5 and mGlu7 receptors. Promotes cognitive flexibility in a rat model.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 353229-59-1
Molecular Formula C21H20ClF3N2O4S

Specifications

Quantity 50 mg
Formula Weight 488.91
Purity >99%
Molecular Weight (g/mol) 488.906
Chemical Name or Material LY 487379 hydrochloride
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