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Tocris Bioscience™ Lopinavir
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Product Code. 18775986
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Quantity:
50 mg
Unit Size:
50mg
Product Code. Quantity unitSize
18775986 50 mg 50mg
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Product Code. 18775986

Brand: Tocris Bioscience™ 7052/50

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74.80 EUR valid until 2026-03-31
BEST PRICE on Promo! Use promo code "27931" to get your promotional price.
This item is not returnable. View return policy

Description

Highly potent and selective HIV-1 protease inhibitor

Lopinavir is a highly potent and selective HIV-1 protease inhibitor (IC50 = 6.5 nM, HIV cultured in peripheral blood mononuclear cells; Ki = 1.3 pM). Displays >105-fold selectivity for HIV-1 protease over mammalian proteases including renin and cathepsin D and E. Inhibits HIV-1 protease in patient HIV isolates displaying mutations that confer resistance to ritonavir (Cat. No. 5856) (IC50 values in 5 - 50 nM range). Also inhibits SARS-CoV-2 replication in vitro (IC50 = 26 μM)
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Specifications

Chemical Name or Material (αS)-N-[(1 S,3 S,4 S)-4-[[2-(2,6-Dimethylphenoxy)acetyl]amino]-3-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]tetrahydro-α-(1-methylethyl)-2-oxo-1(2 H)-pyrimidineacetamide
CAS 192725-17-0
Quantity 50 mg
Target Additional Synthetic Protease Inhibitors
Molecular Formula C37H48N4O5
Purity 0.98
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