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L-Glutathione, reduced, 98+%

Product Code. 15494589
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Product Code. 15494589 Supplier Thermo Scientific Alfa Aesar Supplier No. J62166.14
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Description

A tripeptide used for reductive cleavage of disulfide bonds | CAS: 70-18-8 | C10H17N3O6S | 307.321 g/mol

A tripeptide used for the reductive cleavage of disulfide bonds L-Glutathione is used in the treatment of lung diseases for patients who are HIV positive. It protects the cancerous cells by conferring resistance to chemotherapeutic drugs. It is involved in many aspects of metabolism including transport of g-glutanyl amino acids and reductive cleavage of disulfide bonds. As an antioxidant, it prevents damage to important cellular components that arise due to reactive oxygen species like free radicals and peroxide. It is also used to decrease the concentrations of inflammatory cytokines (IL-6, IL-18) as well as involved in increasing the level of serum Ca2+ ions. It is also used in white wine production.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, dimethyl formamide, ethanol, phosphate buffered saline, diluted alcohol, liquid ammonia and dimethyl sulfoxide.

Notes
Store in cool place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 70-18-8
Molecular Formula C10H17N3O6S
Molecular Weight (g/mol) 307.321
MDL Number MFCD00065939
InChI Key RWSXRVCMGQZWBV-WDSKDSINSA-N
Synonym glutathione, l-glutathione, glutathion, glutathione-sh, glutinal, isethion, tathion, reduced glutathione, deltathione, neuthion
PubChem CID 124886
ChEBI CHEBI:16856
IUPAC Name (2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-1-oxo-3-sulfanylpropan-2-yl]amino]-5-oxopentanoic acid
SMILES C(CC(=O)NC(CS)C(=O)NCC(=O)O)C(C(=O)O)N

Specifications

Melting Point ∽193°C (decomposition)
Color White
Quantity 25 g
Beilstein 1729812
Merck Index 14,4475
Solubility Information Soluble in water,dimethyl formamide,ethanol,phosphate buffered saline,diluted alcohol,liquid ammonia and dimethyl sulfoxide.
Optical Rotation −17° (c=2 in Water)
Formula Weight 307.33
Percent Purity ≥98%
Physical Form Crystalline Powder
Chemical Name or Material L-Glutathione, reduced
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