missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. STEMCELL Technologies Genistein

STEMCELL Technologies Genistein

Product Code. 17110012
Encompass_Preferred
Change view
Click to view available options
Quantity:
100 mg
250 mg
Unit Size:
100mg
250mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
17110012 100 mg 100mg
17120012 250 mg 250mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 17110012 Supplier STEMCELL Technologies Supplier No. 72002

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

NF-kB, AMPK, and tyrosine kinase pathway inhibitor; Inhibits tyrosine kinase, topoisomerase II and activates PPARγ

  • Genistein is a phytoestrogen that exhibits a wide range of biological effects
  • It acts by competing for the ATP-binding site of tyrosine kinases but does not inhibit the activity of serine- and threonine-specific kinases such as cAMP-dependent protein kinase, protein kinase C, and phosphorylase kinase (Akiyama et al.) Genistein binds to and activates peroxisome proliferator-activated receptor-gamma (PPARγ) and estrogen receptors, leading to a decrease in osteogenesis and an increase in adipogenesis (Dang et al.) Genistein also binds and activates the seven-transmembrane estrogen receptor GPR30 to activate alternative estrogen signaling pathways (Thomas & Dong)
  • Inhibits adipocyte differentiation in 3T3-L1 cell culture (Hwang et al.)
  • Control of osteoblast and adipocyte cell fates in mouse bone marrow cells (Dang et al.)
  • Inhibits growth of leukemia, lymphoma, neuroblastoma, gastric, breast, and prostate cancer cells (Sarkar & Li)

Specifications

CAS 446-72-0
Quantity 100 mg
Molecular Formula C15H10O5
Purity ≥98%
Produkttitel
Välj ett problem

Genom att klicka på Skicka bekräftar du att du kan bli kontaktad av Fisher Scientific angående feedbacken du har lämnat i detta formulär. Vi kommer inte att dela din information för andra ändamål. All kontaktinformation som tillhandahålls ska också underhållas i enlighet med vår Sekretesspolicy.