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Filaggrin Antibody (FLG/1562), Novus Biologicals™

Product Code. 18215030 Shop All Bio Techne Products
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18215030 20 μg 20µg
18071384 100 μg 100µg
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Product Code. 18215030 Supplier Novus Biologicals Supplier No. NBP25324520UG
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Estimated Shipment: 10-08-2026
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Description

Mouse Monoclonal Antibody

Filaggrin Monoclonal specifically detects Filaggrin in Human samples. It is validated for Immunocytochemistry/Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Filaggrin
Applications Immunocytochemistry, Immunofluorescence, Immunohistochemistry
Classification Monoclonal
Clone FLG/1562
Concentration 0.2 mg/mL
Conjugate Unconjugated
Dilution Flow Cytometry 0.5 - 1 ug/million cells, Immunocytochemistry/Immunofluorescence 1 - 2 ug/ml, Immunohistochemistry-Paraffin 0.5 - 1.0 ug/ml, SDS-Page
Formulation 10mM PBS with 0.05% BSA with 0.05% Sodium Azide
Gene Alias ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Gene Symbols FLG
Host Species Mouse
Immunogen Recombinant human Filaggrin protein fragment (aa 198-288) (exact sequence is proprietary)
Purification Method Protein A or G purified
Quantity 20 μg
Regulatory Status RUO
Research Discipline Cytoskeleton Markers
Primary or Secondary Primary
Gene ID (Entrez) 2312
Test Specificity Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Target Species Human
Content And Storage Store at 4C.
Form Purified
Isotype IgG1 κ
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For Research Use Only

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