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Tocris Bioscience™ CNQX
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Product Code. 30001060
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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
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Product Code. 30001060

Brand: Tocris Bioscience™ 0190/50

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This item is not returnable. View return policy

Description

Potent and selective non-NMDA iGluR antagonist

CNQX is an AMPA and kainate receptor antagonist (IC50 values are 0.3 μM and 1.5 μM for AMPA and kainate receptors, respectively). CNQX is also an antagonist at the glycine modulatory site on the NMDA receptor complex (IC50 = 25 μM). CNQX can be used to isolate GABAA receptor-mediated spontaneous inhibitory postsynaptic currents and antagonizes non-NMDA receptor-mediated responses in cultured cerebellar granule cells. CNQX shows neuroprotective effects in models of ischemia and inhibits seizure-like activity in hippocampal neurons.

CNQX Disodium Salt (Cat. No. 1045) also available.

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Chemical Identifiers

CAS 115066-14-3
Molecular Formula C9H4N4O4

Specifications

Quantity 50 mg
Formula Weight 232.16
Purity >99%
Molecular Weight (g/mol) 232.155
Chemical Name or Material CNQX
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