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Clathrin light chain Antibody (CLC/1421), DyLight 594, Novus Biologicals™

Product Code. 18214814 Shop All Bio Techne Products
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Product Code. 18214814 Supplier Novus Biologicals Supplier No. NBP254436DL594
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Estimated Shipment: 03-08-2026
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Mouse Monoclonal Antibody

Clathrin light chain Monoclonal specifically detects Clathrin light chain in Human samples. It is validated for Immunohistochemistry, Immunohistochemistry (Paraffin).
TRUSTED_SUSTAINABILITY

Specifications

Antigen Clathrin light chain
Applications Immunohistochemistry, Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone CLC/1421
Conjugate DyLight 594
Dilution Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Formulation 50mM Sodium Borate with 0.05% Sodium Azide
Gene Alias clathrin light chain A, clathrin, light chain A, LCA, light polypeptide (Lca)
Gene Symbols CLTA
Host Species Mouse
Immunogen Purified recombinant N-terminal fragment of human Clathrin Light Chain
Purification Method Protein A or G purified
Quantity 0.1 mL
Regulatory Status RUO
Research Discipline Membrane Trafficking and Chaperones, Membrane Vesicle Markers
Primary or Secondary Primary
Test Specificity Recognizes proteins of 31-44kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60% homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
Target Species Human
Content And Storage Store at 4°C in the dark.
Isotype IgG2b κ
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