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STEMCELL Technologies Bafilomycin A1

Product Code. 17140352
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500 μg
Unit Size:
500µg
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17140352 500 μg 500µg
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Product Code. 17140352 Supplier STEMCELL Technologies Supplier No. 74242

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Description

Inhibits autophagy and vacuolar H+-ATPase (V-ATPase)

  • Bafilomycin A1 is a macrolide antibiotic drug and autophagy inhibitor
  • It prevents the acidification of autophagosomes via the inhibition of vacuolar H+-ATPase (V-ATPase; Klionsky et al.)
  • Inhibits the proteolytic degradation associated with autophagy in human mesenchymal stem cells (Oliver et al.)
  • At low concentrations, it inhibits autophagy and promotes apoptotic cell death in pediatric B cell acute lymphoblastic leukemia (B-ALL) cells (Yuan et al.)

Specifications

CAS 88899-55-2
Synonym NSC 381866
Quantity 500 μg
Molecular Formula C35H58O9
Purity ≥95%
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