missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. 30002071

Tocris Bioscience™ AX 15836, > 98%
GREENER_CHOICE

Product Code. 30002071
Change view
Click to view available options
Quantity:
10 mg
Unit Size:
10mg
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
30002071 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
This item is not returnable. View return policy
Product Code. 30002071 Supplier Tocris Bioscience™ Supplier No. 5843/10

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Potent and selective ERK5 inhibitor

Potent and selective ERK5 inhibitor (IC50 = 8 nM). Exhibits >1,000-fold selectivity for ERK5 over a panel of over 200 kinases. Also exhibits selectivity over bromodomain BRD4 (Kd = 3,600 nM). Increases vomocytosis in human macrophages in vitro, as well as in an in vivo zebrafish model of cryptococcal disease, reducing spread of infection.
TRUSTED_SUSTAINABILITY

Specifications

CAS 2035509-96-5
Quantity 10 mg
Solubility Soluble to 100mM in 1eq. HCl and to 100mM in DMSO
Molecular Formula C32H40N8O5S
Formula Weight 648.78
Purity >98%
Molecular Weight (g/mol) 648.78
Chemical Name or Material 5,11-Dihydro-2-[[2-ethoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5-meth
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.