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  5. Tocris Bioscience™ 6-Hydroxy-DL-DOPA

Tocris Bioscience™ 6-Hydroxy-DL-DOPA
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Product Code. 18785308
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18785308 10 mg 10mg
18734049 50 mg 50mg
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Product Code. 18785308 Supplier Tocris Bioscience™ Supplier No. 5740/10

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Description

Allosteric inhibitor of RAD52; also APE1 inhibitor

6-Hydroxy-DL-DOPA is an allosteric inhibitor of RAD52; inhibits RAD52 binding to single strand DNA binding domains (IC50 = 1.1 μM). Selectively inhibits proliferation of BRCA-deficient cancer cells in vitro. Also inhibits APE1.
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Specifications

Chemical Name or Material 2,5-Dihydroxy-DL-tyrosine
CAS 21373-30-8
Quantity 10 mg
Target DNA, RNA and Protein Synthesis Inhibitors
Molecular Formula C9H11NO5
Formula Weight 213.19
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