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Tocris Bioscience™ 5-Iodotubercidin
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Product Code. 18054072
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Product Code. 18054072 Supplier Tocris Bioscience™ Supplier No. 1745/1
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Estimated Shipment: 21-09-2026
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This item is not returnable. View return policy
To receive the discount customers must purchase three of the same product at list price in a single order to receive 33.33% discount. There is no limit to the multiples of 3 that customers can buy. Use promo code ”27950” to get your promotional price

Beschreibung

Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases

Potent adenosine kinase inhibitor (IC50 = 26 nM). Also nucleoside transporter inhibitor (IC50 values are < 25 nM, 7 μM and 15 μM for inhibition of [3H]adenosine, [3H]uridine and [3H]formycin B uptake respectively). Strongly stimulates glycogen synthesis in hepatocytes via activation of glycogen synthase. Also inhibits CK1, insulin receptor tyrosine kinase, phosphorylase kinase, PKA, CK2 and PKC (IC50 values are 0.4, 3.5, 5-10, 5-10, 10.9 and 27.7 μM respectively). Decreases hippocampal DNA methylation through adenosine kinase inhibition in vivo.
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Spezifikation

CAS 24386-93-4
Quantity 1 mg
Molecular Formula C11H13IN4O4
Formula Weight 392.15
Purity 97%
Molecular Weight (g/mol) 392.15
Chemical Name or Material 5-Iodotubercidin
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