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4-Aminopyridine, 98%
Description
It is used as a research tool, in characterizing subtypes of the potassium channel. It has also been used as a drug, to manage some of the symptoms of multiple sclerosis. In the laboratory, 4-AP is a useful pharmacological tool in studying various potassium conductances in physiology and biophysics. Spinal cord injury patients have also seen improvement with 4-AP therapy.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Soluble in water(112 g/L at 20 deg C). Soluble in ethyl ether, benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol, acetone, tetrahydrofuran, isopropanol, acetonitrile, N,N-dimethylformamide, dimethylsulfoxide, and ethanol.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Specifications
Specifications
| Melting Point | 157°C to 161°C |
| Density | 1.26 |
| Boiling Point | 273°C to 274°C |
| Flash Point | 164°C (327°F) |
| Odor | Unpleasant |
| Quantity | 50 g |
| UN Number | UN2671 |
| Beilstein | 105782 |
| Merck Index | 14,3933 |
| Solubility Information | Soluble in water(112g/L at 20 deg C). Soluble in ethyl ether,benzene. Slightly soluble in ligroin. Very soluble in ethanol. Soluble in methanol,acetone,tetrahydrofuran,isopropanol,acetonitrile,N,N-dimethylformamide,dimethylsulfoxide,and ethanol. |
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Safety and Handling
- 4-Aminopyridine
- Danger
- Acute toxicity Category 2
- Acute toxicity Category 3
- LONG-TERM AQUATIC HAZARD Chronic 2
- Serious eye damage/eye irritation Category 1
- Skin corrosion/irritation Category 1 B
- H300-Fatal if swallowed.
- H311-Toxic in contact with skin.
- H314-Causes severe skin burns and eye damage.
- H318-Causes serious eye damage.
- H331-Toxic if inhaled.
- H411-Toxic to aquatic life with long lasting effects.
- P280-Wear protective gloves/protective clothing/eye protection/face protection.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
- P304+P340-IF INHALED: Remove person to fresh air and keep comfortable for breathing.
- P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P310-Immediately call a POISON CENTER/doctor/.
- MIXTURE LIST-Contains : 4-Aminopyridine
RUO – Research Use Only
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