CAS RN 853299-07-7

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Tocris Bioscience™ K 03861

Potent CDK2 inhibitor

Pricing and Availability
Specifications

Target	Cyclin-dependent Kinase Inhibitors
CAS	853299-07-7
Purity	0.98
Chemical Name or Material	N-[4-[(2-Amino-4-pyrimidinyl)oxy]phenyl]-N'-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]urea
Recommended Storage	Store at -20°C
Molecular Formula	C₂₄H₂₆F₃N₇O₂

AUZ 454, MedChemExpress

MedChemExpress AUZ 454 (K03861) is a type II CDK2 inhibitor with Kd of 8.2 nM. AUZ 454 (K03861) inhibits CDK2 activity by competing with binding of activating cyclins.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	501.5
Color	Off-White
Physical Form	Solid
Chemical Name or Material	AUZ 454
Grade	Research
SMILES	NC1=NC(OC2=CC=C(NC(NC3=CC(C(F)(F)F)=C(CN4CCN(C)CC4)C=C3)=O)C=C2)=CC=N1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.91%
CAS	853299-07-7
Solubility Information	DMSO : 250 mg/mL (498.50 mM; Need ultrasonic)
Synonym	K03861
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₄H₂₆F₃N₇O₂
Formula Weight	501.5

CAS RN 853299-07-7

CAS RN 853299-07-7

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Tocris Bioscience™ K 03861 Greener Choice ProductThis product offers one or more environmental benefits itemized in the U.S. FTC “Green Guides.”Learn More About the Greener Choice Program

Tocris Bioscience™ K 03861