CAS RN 852808-04-9

1 – 2 of 2 results

ABT 737, TRC

CAS: 852808-04-9 Molecular Formula: C42 H45 Cl N6 O5 S2 Molecular Weight (g/mol): 813.43 IUPAC Name: 4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide SMILES: CN(C)CC[C@H](CSc1ccccc1)Nc2ccc(cc2[N+](=O)[O-])S(=O)(=O)NC(=O)c3ccc(cc3)N4CCN(Cc5ccccc5c6ccc(Cl)cc6)CC4

Pricing and Availability
Specifications

CAS	852808-04-9
Molecular Weight (g/mol)	813.43
SMILES	CN(C)CC[C@H](CSc1ccccc1)Nc2ccc(cc2[N+](=O)[O-])S(=O)(=O)NC(=O)c3ccc(cc3)N4CCN(Cc5ccccc5c6ccc(Cl)cc6)CC4
IUPAC Name	4-[4-[[2-(4-chlorophenyl)phenyl]methyl]piperazin-1-yl]-N-[4-[[(2R)-4-(dimethylamino)-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
Molecular Formula	C42 H45 Cl N6 O5 S2

ABT-737, MedChemExpress

MedChemExpress ABT-737, a BH3 mimetic, is a potent Bcl-2, Bcl-xL and Bcl-w inhibitor with EC50s of 30.3 nM, 78.7 nM, and 197.8 nM, respectively. ABT-737 induces the disruption of the BCL-2/BAX complex and BAK-dependent but BIM-independent activation of the intrinsic apoptotic pathway. ABT-737 induces autophagy and has the potential for acute myeloid leukemia (AML) research.

Pricing and Availability
Specifications

Molecular Weight (g/mol)	813.43
Color	Orange Red
Physical Form	Solid
Chemical Name or Material	ABT-737
Grade	Research
SMILES	CN(CC[C@@H](NC1=CC=C(C=C1[N+]([O-])=O)S(NC(C2=CC=C(C=C2)N3CCN(CC3)CC4=CC=CC=C4C5=CC=C(C=C5)Cl)=O)(=O)=O)CSC6=CC=CC=C6)C
For Use With (Application)	Cancer-programmed cell death
Percent Purity	98.38%
CAS	852808-04-9
Solubility Information	DMSO : 50 mg/mL (61.47 mM; Need ultrasonic)
Health Hazard 1	H302∣H315∣H319∣H335
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₄₂H₄₅ClN₆O₅S₂
Formula Weight	813.43

CAS RN 852808-04-9

Filtered Search Results

Narrow Results