CAS RN 851881-60-2

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ADX-47273, MedChemExpress

MedChemExpress ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities.

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Molecular Weight (g/mol)	369.36
Color	White
Physical Form	Solid
Chemical Name or Material	ADX-47273
Grade	Research
SMILES	O=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2
For Use With (Application)	Neuroscience-Neuromodulation
Percent Purity	99.18%
CAS	851881-60-2
Solubility Information	DMSO : ≥ 31 mg/mL (83.93 mM)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₁₇F₂N₃O₂
Formula Weight	369.36

CAS RN 851881-60-2

CAS RN 851881-60-2

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