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ADX-47273, MedChemExpress

Product Code. 16475518
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Product Code. 16475518

Brand: Medchem Express HY13058

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Description

MedChemExpress ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities.

ADX-47273 is a potent, selective and brain-penetrant mGluR5 positive allosteric modulator (PAM), with an EC50 of 0.17 μM for potentiation of glutamate (50 nM) response. ADX-47273 has antipsychotic and procognitive activities.

Specifications

Chemical Name or Material ADX-47273
CAS 851881-60-2
Color White
Purity Grade Notes Research
Molecular Formula C20H17F2N3O2
Quantity 10 mg
Solubility Information DMSO : ≥ 31 mg/mL (83.93 mM)
SMILES O=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2
Molecular Weight (g/mol) 369.36
Formula Weight 369.36
Percent Purity 99.18%
Grade Research
Physical Form Solid
For Use With (Application) Neuroscience-Neuromodulation
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Research purposes only

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