MedChemExpress Columbin is an orally active diterpenoid furanolactone from Calumbae radix, has anti-inflammatory and anti-trypanosomal effects. Columbin selectively inhibits COX-2 (EC50=53.1 μM) over COX-1 (EC50=327 μM).

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Specifications

Molecular Weight (g/mol)	358.39
Color	White
Physical Form	Solid
Chemical Name or Material	Columbin
Grade	Research
SMILES	O=C1[C@](C=C2)(O)[C@@](CC3)(C)[C@@]([C@@](C[C@@H](C4=COC=C4)O5)(C)[C@]3([H])C5=O)([H])[C@]2([H])O1
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.77%
CAS	546-97-4
Solubility Information	DMSO : ≥ 100 mg/mL (279.03 mM)
Health Hazard 1	H315∣H319
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₀H₂₂O₆
Formula Weight	358.39

CAS RN 546-97-4

CAS RN 546-97-4

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