CAS RN 1648863-90-4

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High affinity group 1 PAK inhibitor

CAS	1648863-90-4
Chemical Name or Material	8-[(trans-5-Amino-1,3-dioxan-2-yl)methyl]-6-[2-chloro-4-(6-methyl-2-pyridinyl)phenyl]-2-(methylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one
Recommended Storage	Store at -20°C
Molecular Formula	C₂₅H_25ClN₆O₃
Formula Weight	Observed MW: 492.96
Assay Percent Range	>98%

MedChemExpress G-5555 is a potent p21-activated kinase 1 (PAK1) inhibitor with Kis of 3.7 nM and 11 nM for PAK1 and PAK2, respectively.

Molecular Weight (g/mol)	492.96
Color	Light Yellow
Physical Form	Powder
Chemical Name or Material	G-5555
Grade	Research
SMILES	ClC(C=C(C1=NC(C)=CC=C1)C=C2)=C2C3=CC4=CN=C(NC)N=C4N(C[C@@H]5OC[C@@H](N)CO5)C3=O
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.0%
CAS	1648863-90-4
Solubility Information	DMSO : 25 mg/mL (50.71 mM; ultrasonic and warming and heat to 80°C)
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₅H₂₅ClN₆O₃
Formula Weight	492.96

High affinity group I PAK inhibitor

High affinity group I PAK inhibitor