CAS RN 1643368-58-4

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MedChemExpress BMS-986142 is a potent and highly selective reversible inhibitor of Bruton's tyrosine kinase (BTK) with an IC50 of 0.5 nM.

Molecular Weight (g/mol)	572.6
Color	White
Physical Form	Solid
Chemical Name or Material	BMS-986142
Grade	Research
SMILES	O=C1C2=C(C(F)=CC=C2)N(C)C(N1C3=C(C)[C@]([C@]4=C(F)C=C(C(N)=O)C5=C4C6=C(C[C@@H](C(C)(C)O)CC6)N5)=CC=C3)=O
For Use With (Application)	COVID-19-immunoregulation
Percent Purity	99.53%
CAS	1643368-58-4
Solubility Information	DMSO : 125 mg/mL (218.30 mM; Need ultrasonic)
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₃₂H₃₀F₂N₄O₄
Formula Weight	572.6