CAS RN 1421693-22-2

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CDKI-73, MedChemExpress

MedChemExpress CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. CDKI-73 down-regulates the RNAPII phosphorylation. CDKI-73 is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion.

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Specifications

Molecular Weight (g/mol)	394.45
Color	Light Yellow
Physical Form	Solid
Chemical Name or Material	CDKI-73
Grade	Research
SMILES	CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1
For Use With (Application)	Cancer-Kinase/protease
Percent Purity	98.36%
CAS	1421693-22-2
Solubility Information	DMSO : ≥ 52 mg/mL (131.83 mM)
Synonym	LS-007
Purity Grade Notes	Research
Recommended Storage	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Shelf Life	4°C, stored under nitrogen∣In solvent : -80°C, 6 months∣-20°C, 1 month (stored under nitrogen)
Molecular Formula	C₁₅H₁₅FN₆O₂S₂
Formula Weight	394.45

CAS RN 1421693-22-2

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