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CDKI-73, MedChemExpress

Product Code. 16485168
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Product Code. 16485168 Supplier Medchem Express Supplier No. HY12445

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MedChemExpress CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. CDKI-73 down-regulates the RNAPII phosphorylation. CDKI-73 is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion.

CDKI-73 (LS-007) is an orally active and highly efficacious CDK9 inhibitor, with Ki values of 4 nM, 4 nM and 3 nM for CDK9, CDK1 and CDK2, respectively. CDKI-73 down-regulates the RNAPII phosphorylation. CDKI-73 is also a novel pharmacological inhibitor of Rab11 cargo delivery and innate immune secretion.

Specifications

Chemical Name or Material CDKI-73
CAS 1421693-22-2
Color Light Yellow
Purity Grade Notes Research
Molecular Formula C15H15FN6O2S2
Quantity 10 mg
Synonym LS-007
Solubility Information DMSO : ≥ 52 mg/mL (131.83 mM)
SMILES CNC1=NC(C)=C(C2=C(F)C=NC(NC3=CC(S(=O)(N)=O)=CC=C3)=N2)S1
Molecular Weight (g/mol) 394.45
Formula Weight 394.45
Percent Purity 98.36%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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