CAS RN 1038915-73-9

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Molecular Weight (g/mol)

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Niraparib Tosylate, TRC

High-purity organic molecules and analytical standards, strategically delivered worldwide to empower innovation and commercial success.

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Niraparib tosylate, MedChemExpress

MedChemExpress Niraparib tosylate (MK-4827 tosylate) is a highly potent and orally bioavailable PARP1 and PARP2 inhibitor with an IC50 of 3.8 and 2.1 nM, respectively. Niraparib tosylate leads to inhibition of repair of DNA damage, activates apoptosis and shows anti-tumor activity.

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Specifications

Molecular Weight (g/mol)	492.59
Color	White
Physical Form	Solid
Chemical Name or Material	Niraparib tosylate
Grade	Research
SMILES	NC(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C21)=O.O=S(C5=CC=C(C)C=C5)(O)=O
For Use With (Application)	Cancer-programmed cell death
Percent Purity	95.0%
CAS	1038915-73-9
Solubility Information	DMSO : 100 mg/mL (203.01 mM; ultrasonic and warming and heat to 60°C) ∣H2O : 1 mg/mL (2.03 mM; heat to 50°C)
Synonym	MK-4827 tosylate
Purity Grade Notes	Research
Recommended Storage	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Shelf Life	4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)
Molecular Formula	C₂₆H₂₈N₄O₄S
Formula Weight	492.59

CAS RN 1038915-73-9

CAS RN 1038915-73-9

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