CAS RN 102121-60-8

IUPAC Name: 4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-amido)benzoic acid

Synonyms: 4-(5,5,8,8-tetramethyl-6,7-dihydronaphthalene-2-amido)benzoic acid

Molecular Weight (g/mol): 351.45

Molecular Formula: C22H25NO3

InChi Key: SZWKGOZKRMMLAJ-UHFFFAOYSA-N

SMILES: CC1(C)CCC(C)(C)C2=CC(=CC=C12)C(=O)NC1=CC=C(C=C1)C(O)=O

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CAS: 102121-60-8 Molecular Formula: C22H25NO3

CAS	102121-60-8
Molecular Formula	C22H25NO3

Retinoid pathway activator; Activates retinoic acid receptor (RAR) alpha

MedChemExpress AM580 is a selective RARα agonist with IC50 and EC50 of 8 nM and 0.36 nM, respectively.

Molecular Weight (g/mol)	351.44
Color	White
Physical Form	Solid
Chemical Name or Material	AM580
Grade	Research
SMILES	CC(CC1)(C)C2=C(C=CC(C(NC3=CC=C(C(O)=O)C=C3)=O)=C2)C1(C)C
For Use With (Application)	Cancer-programmed cell death
Percent Purity	99.46%
CAS	102121-60-8
Solubility Information	DMSO : ≥ 45 mg/mL (128.04 mM) ∣H2O : < 0.1 mg/mL (insoluble)
Health Hazard 1	H302∣H315∣H319∣H335
Synonym	CD336 NSC608001 Ro 40-6055
Purity Grade Notes	Research
Recommended Storage	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life	Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula	C₂₂H₂₅NO₃
Formula Weight	351.44

AM 580 synthesized to Ancillary Material Grade