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Benzenesulfonamides

Organic compounds that consist of a benzene ring substituted with a sulfonyl group that is subsequently bonded to an amino group; considered the amide of benzenesulfonic acid.

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1 – 15 of 235 results
1

Hydroxyhexamide, MedChemExpress

MedChemExpress Hydroxyhexamide is a pharmacologically active metabolite of Acetohexamide, used as a hypoglycemic agents.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 326.41
Color White
Physical Form Solid
Chemical Name or Material Hydroxyhexamide
Grade Research
SMILES O=S(C1=CC=C(C(O)C)C=C1)(NC(NC2CCCCC2)=O)=O
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.68%
CAS 3168-01-2
Solubility Information DMSO : ≥ 300 mg/mL (919.09 mM)
Synonym (±)-Hydroxyhexamid
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C15H22N2O4S
Formula Weight 326.41
2

AZD2098, MedChemExpress

MedChemExpress AZD2098 is a potent and selective CC-chemokine receptor 4 (CCR4) inhibitor with pIC50s of 7.8, 8.0, 8.0 and 7.6 for human, rat, mouse and dog respectively, used for asthma research.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 334.18
Color White
Physical Form Solid
Chemical Name or Material AZD2098
Grade Research
SMILES O=S(C1=CC=CC(Cl)=C1Cl)(NC2=NC=CN=C2OC)=O
For Use With (Application) COVID-19-immunoregulation
Percent Purity 99.86%
CAS 566203-88-1
Solubility Information DMSO : 100 mg/mL (299.24 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C11H9Cl2N3O3S
Formula Weight 334.18
3

Acetohexamide, MedChemExpress

MedChemExpress Acetohexamide is a first-generation sulfonylurea medication used to treat diabetes mellitus type 2; stimulate the pancreas to secrete insulin.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 324.4
Color White
Physical Form Solid
Chemical Name or Material Acetohexamide
Grade Research
SMILES O=S(C1=CC=C(C(C)=O)C=C1)(NC(NC2CCCCC2)=O)=O
For Use With (Application) Cancer-programmed cell death
Percent Purity 99.39%
CAS 968-81-0
Solubility Information DMSO : 25 mg/mL (77.07 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C15H20N2O4S
Formula Weight 324.4
4

Orexin 2 Receptor Agonist, MedChemExpress

MedChemExpress Orexin 2 Receptor Agonist is a potent (EC50 on OX2R is 23 nM) and OX2R-selective (OX1R/OX2R EC50 ratio is 70) agonist.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 586.7
Color White
Physical Form Solid
Chemical Name or Material Orexin 2 Receptor Agonist
Grade Research
SMILES O=C(C1=CC=CC(C)=C1)NCCNC2=CC(NS(C3=C(OC)C=CC(C4=CC(C(N(C)C)=O)=CC=C4)=C3)(=O)=O)=CC=C2
For Use With (Application) Neuroscience-Neuromodulation
Percent Purity 99.75%
CAS 1796565-52-0
Solubility Information DMSO : ≥ 32 mg/mL (54.54 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C32H34N4O5S
Formula Weight 586.7
5

SU11274, MedChemExpress

MedChemExpress SU11274 is a selective Met inhibitor with IC50 of 10 nM, but has no effects on PGDFRβ, EGFR or Tie2.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 568.09
Color Orange
Physical Form Solid
Chemical Name or Material SU11274
Grade Research
SMILES O=S(C1=CC2=C(C=C1)NC(/C2=C/C3=C(C(C(N4CCN(CC4)C)=O)=C(N3)C)C)=O)(N(C)C5=CC=CC(Cl)=C5)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.19%
CAS 658084-23-2
Solubility Information DMSO : ≥ 100 mg/mL (176.03 mM)
Synonym PKI-SU11274
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C28H30ClN5O4S
Formula Weight 568.09
6

TG101209, MedChemExpress

MedChemExpress TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 509.67
Color Gray
Physical Form Solid
Chemical Name or Material TG101209
Grade Research
SMILES O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C2C)=C1)(NC(C)(C)C)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.81%
CAS 936091-14-4
Solubility Information DMSO : ≥ 50 mg/mL (98.10 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C26H35N7O2S
Formula Weight 509.67
7

LX2343, MedChemExpress

MedChemExpress LX2343 is a BACE1 enzyme inhibitor with an IC50 value of 11.43±0.36 μM. LX2343 acts as a non-ATP competitive PI3K inhibitor with an IC50 of 15.99±3.23 μM. LX2343 stimulates autophagy in its promotion of Aβ clearance.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 474.91
Color White
Physical Form Solid
Chemical Name or Material LX2343
Grade Research
SMILES O=C(NC1=CC=C(OCO2)C2=C1)CN(C3=CC(Cl)=CC=C3OC)S(=O)(C4=CC=CC=C4)=O
For Use With (Application) Neuroscience-Neurodegeneration
Percent Purity 99.74%
CAS 333745-53-2
Solubility Information DMSO : ≥ 100 mg/mL (210.57 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C22H19ClN2O6S
Formula Weight 474.91
8

HMN-176, MedChemExpress

MedChemExpress HMN-176 is a stilbene derivative which inhibits mitosis, interfering with polo-like kinase-1 (plk1), without significant effect on tubulin polymerization.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 382.43
Color Light Yellow
Physical Form Solid
Chemical Name or Material HMN-176
Grade Research
SMILES O=S(C1=CC=C(OC)C=C1)(NC2=CC=CC=C2/C=C/C3=CC=N(C=C3)=O)=O
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.54%
CAS 173529-10-7
Solubility Information DMSO : ≥ 30 mg/mL (78.45 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C20H18N2O4S
Formula Weight 382.43
9

PF-06471553, MedChemExpress

MedChemExpress PF-06471553 is a potent, selective and orally available monoacylglycerol acyltransferase 3 (MGAT3) inhibitor, with an IC50 of 92 nM.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 467.54
Color White
Physical Form Solid
Chemical Name or Material PF-06471553
Grade Research
SMILES O=S(C1=CC2=C(CN(C(CC3=CC=CC(OC)=C3)=O)C2)C=C1)(NC4=NN(C5CCC5)N=C4)=O
For Use With (Application) Metabolism-sugar/lipid metabolism
Percent Purity 98.18%
CAS 1808094-07-6
Solubility Information DMSO : ≥ 150 mg/mL (320.83 mM)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C23H25N5O4S
Formula Weight 467.54
10

Etebenecid, MedChemExpress

MedChemExpress Etebenecid is a uricosuric agents, lower uric acid levels in the body by increasing the elimination of uric acid by the kidneys, also inhibits penicillin tubular secretion.

ENCOMPASS_PREFERRED
11

Alofanib, MedChemExpress

MedChemExpress Alofanib (RPT835) is a potent and selective allosteric inhibitor of fibroblast growth factor receptor 2 (FGFR2). Anticancer and antiangiogenic activity.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 413.4
Color Yellow
Physical Form Solid
Chemical Name or Material Alofanib
Grade Research
SMILES O=C(O)C1=CC=CC(S(=O)(NC2=CC(C3=CC=CN=C3)=C(C)C=C2[N+]([O-])=O)=O)=C1
For Use With (Application) Cancer-Kinase/protease
Percent Purity 98.81%
CAS 1612888-66-0
Solubility Information DMSO : ≥ 30.1 mg/mL (72.81 mM)
Synonym RPT835
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C19H15N3O6S
Formula Weight 413.4
12

PKR-IN-2, MedChemExpress

MedChemExpress PKR-IN-2 is a pyruvate kinase isoform PKR activator extracted from patent WO2014139144A1, compound 160. PKR-IN-2 can be used for the research of PKR function related diseases, including cancer, diabetes, obesity, autoimmune disorders, and benign prostatic hyperplasia.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 468.57
Color White
Physical Form Solid
Chemical Name or Material PKR-IN-2
Grade Research
SMILES N1C2C(=C(S(NC3=CC=C(C(N4CCC(O)(CC(C)C)CC4)=O)C=C3)(=O)=O)C=CC=2)N=CC=1
For Use With (Application) Cancer-Kinase/protease
Percent Purity 95.14%
CAS 1628428-01-2
Solubility Information DMSO : 50 mg/mL (106.71 mM; Need ultrasonic)
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C24H28N4O4S
Formula Weight 468.57
13

Veralipride, MedChemExpress

MedChemExpress Veralipride is a D2 receptor antagonist. It is an alternative antidopaminergic treatment for menopausal symptoms.

ENCOMPASS_PREFERRED
Molecular Weight (g/mol) 383.46
Color White
Physical Form Solid
Chemical Name or Material Veralipride
Grade Research
SMILES O=C(NCC1N(CC=C)CCC1)C2=CC(S(=O)(N)=O)=CC(OC)=C2OC
For Use With (Application) Neuroscience-Neurodegeneration
Percent Purity 99.57%
CAS 66644-81-3
Solubility Information DMSO : ≥ 100 mg/mL (260.78 mM)
Synonym (±)-Veralipride LIR166
Purity Grade Notes Research
Recommended Storage Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Shelf Life Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Molecular Formula C17H25N3O5S
Formula Weight 383.46
14

L755507, MedChemExpress

MedChemExpress L755507 is a potent, selective agonist of β3-AR with an IC50 of 35 nM. L755507 enhances the homology-directed repair (HDR)-mediated genome editing in CRISPR/Cas9 nickase system.

ENCOMPASS_PREFERRED
15

Sulfamethoxypyridazine, MedChemExpress

MedChemExpress Sulfamethoxypyridazine is a long-acting sulfonamide antibiotic, for treatment of Dermatitis herpetiformis.

ENCOMPASS_PREFERRED