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TG101209, MedChemExpress

Product Code. 16453958
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Product Code. 16453958 Supplier Medchem Express Supplier No. HY10410

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Description

MedChemExpress TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations.

TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM, less potent to Flt3 and RET with IC50 of 25 nM and 17 nM, appr 30-fold selective for JAK2 than JAK3, and sensitive to JAK2V617F and MPLW515L/K mutations.

Specifications

Chemical Name or Material TG101209
CAS 936091-14-4
Color Gray
Purity Grade Notes Research
Molecular Formula C26H35N7O2S
Quantity 10 mg
Solubility Information DMSO : ≥ 50 mg/mL (98.10 mM)
SMILES O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)N4CCN(CC4)C)=NC=C2C)=C1)(NC(C)(C)C)=O
Molecular Weight (g/mol) 509.67
Formula Weight 509.67
Percent Purity 98.81%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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