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Vernakalant Hydrochloride, MedChemExpress

Product Code. 16492127
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Product Code. Quantity unitSize
16492127 50 mg 50mg
16486406 100 mg 100mg
16445988 10 mg 10mg
16438607 5 mg 5mg
16400216 2 mg 2mg
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Product Code. 16492127

Brand: Medchem Express HY14183

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Description

MedChemExpress Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.

Vernakalant hydrochloride is a mixed voltage- and frequency-dependent Na+ and atria-preferred K+ channel blocker. IC50 for block by Vernakalant of wild-type and mutant Kv1.5 channels Fractional block is 13.35±0.93 μM, 0.61±0.03 μM, and 1.63±0.09 μM for Kv1.5 channelwt, Kv1.5 channelI508F, Kv1.5 channelT479A, respectively.

Specifications

Chemical Name or Material Vernakalant Hydrochloride
CAS 748810-28-8
Color Off-White
Purity Grade Notes Research
Molecular Formula C20H32ClNO4
Quantity 50 mg
Synonym RSD1235 hydrochloride
Solubility Information DMSO : 50 mg/mL (129.56 mM; Need ultrasonic) ∣H2O : 50 mg/mL (129.56 mM; Need ultrasonic)
SMILES COC1=C(OC)C=C(CCO[C@H]2[C@H](N3CC[C@@H](O)C3)CCCC2)C=C1.Cl
Molecular Weight (g/mol) 385.93
Formula Weight 385.93
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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