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Varespladib, MedChemExpress

Product Code. 16481827
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Product Code. 16481827 Supplier Medchem Express Supplier No. HY13402

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Description

MedChemExpress Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

Varespladib (LY315920) is a potent and selective group IIA, secretory phospholipase A2 (sPLA2) inhibitor with an IC50 of 9 nM. Varespladib exhibits the significant inhibitory effect on sPLA2 activity in serum from various species including rat, rabbit, guinea pig and human with IC50s of 8.1 nM, 5.0 nM, 3.2 nM and 6.2 nM, respectively.

Specifications

Chemical Name or Material Varespladib
CAS 172732-68-2
Color Off-White
Purity Grade Notes Research
Molecular Formula C21H20N2O5
Quantity 50 mg
Synonym LY315920
Solubility Information DMSO : ≥ 32 mg/mL (84.12 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES O=C(O)COC1=CC=CC2=C1C(C(C(N)=O)=O)=C(CC)N2CC3=CC=CC=C3
Molecular Weight (g/mol) 380.39
Formula Weight 380.39
Percent Purity 98.68%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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