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Gibco™ TrueCut™ Cas9 Protein (Prototype)

Product Code. 17155772
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Quantity:
2.5 mg
5 mg
Unit Size:
2.50mg
5mg
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17155772 5 mg 5mg
17145772 2.5 mg 2.50mg
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Product Code. 17155772 Supplier Gibco™ Supplier No. A45221P

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Description

Gibco TrueCut Cas9 Protein (Prototype) is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency

  • Gibco TrueCut Cas9 Protein (Prototype) is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency.
  • This protein is provided here in a high-concentration, large-scale format as an early-access material for process development.
  • The same high performing enzyme as our TrueCut Cas9 Protein v2, providing superior CRISPR-Cas9 editing efficiency in all tested cell lines, including primary immune cells
  • Developed with protocols and demonstrated performance in editing human primary T cells
  • Provided at a concentration of 10 mg/mL
  • Aseptic manufacturing with sterile filling, bioburden, endotoxin, mycoplasma, residual host nucleic acids, and protein testing
  • Designed to meet United States and European Pharmacopoeia standards for Ancillary Materials for Cell, Gene, and Tissue-engineered Products
  • TrueCut Cas9 Protein (Prototype) is a Streptococcus pyogenes Cas9 (wt) protein, produced by recombinant DNA technology in E. coli for genome editing with CRISPR technology. Cas9 protein forms a very stable RNP complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system. Incorporation of NLS aids delivery to the nucleus, increasing the editing efficiency and on-target cleavage.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 5 mg
Product Type Cas9 Protein
Content And Storage 500 μL TrueCut Cas9 Protein Prototype (10 mg/mL)

Store at -15 to -25°C.
Shipping Condition Dry Ice
Research Category Genome Editing
Product Line TrueCut

For Research Use Only. Not for use in diagnostic procedures. Product is a prototype and performance characteristics of this product have not been established

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