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Thermo Scientific™ Trimethoprim
Trimethoprim, CAS # 738-70-5, is a trimethoxybenzyl-pyrimidine used as an antimicrobial.
Brand: Thermo Scientific™ J63053.03
| Quantity | 1 g |
|---|
This item is not returnable.
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Description
This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.
General Description
• Trimethoprim is a synthetic pyrimidine analog that binds dihydrofolate-reductase and inhibits the synthesis of folic acid; when paired with sulfamethoxazole, its activity is enhanced
• Trimethoprim has antibacterial and antiprotozoal properties
Applications
• Trimethoprim inhibits the conversion of para-aminobenzoic acid (PABA) to folic acid near the end of the synthesis pathway and can be used to study related effects
• Trimethoprim has been radiolabeled and used to trace routes of infection, and it also has been used experimentally as a fluorescent labeler to quantify dihydrofolate-reductase expression
Chemical Identifiers
| 738-70-5 | |
| 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine | |
| Powder | |
| White | |
| Trimethoprim is soluble in water at 0.4 mg/ml; It is also soluble in DMSO at 50 mg/ml and chloroform at 18.2 mg/ml |
| 290.32g/mol | |
| 2°C to 8°C | |
| An antibacterial and inhibitor of formylation. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme | |
| 199°C to 203°C |
Specifications
| 1 g | |
| 2°C to 8°C | |
| An antibacterial and inhibitor of formylation. Dihydrofolate reductase inhibitor with selectivity for the prokaryote enzyme | |
| C14H18N4O3 | |
| 2,4-Diamino-5-(3,4,5-trimethoxybenzyl)pyrimidine | |
| Trimethoprim is soluble in water at 0.4 mg/ml; It is also soluble in DMSO at 50 mg/ml and chloroform at 18.2 mg/ml |
| White | |
| Powder | |
| 738-70-5 | |
| 290.32g/mol | |
| 199°C to 203°C | |
| 625127 |
Safety and Handling
Product Identifier
Signal Word
Hazard Category
Hazard Statement
Precautionary Statement
Supplemental information
- Trimethoprim
Signal Word
- Warning
Hazard Category
- Acute toxicity Category 4
Hazard Statement
- H302-Harmful if swallowed.
Precautionary Statement
- P264-Wash face, hands and anyexposed skin thoroughly after handling.
- P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- P312-Call a POISON CENTER/doctor/if you feel unwell.
Supplemental information
- MIXTURE LIST-Contain: Trimethoprim
Name des Produkts
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