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Invitrogen™ Themis Recombinant Rabbit Monoclonal Antibody (7G7)
Description
Themis Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Flow, ELISA
Themis is a cytoplasmic protein that is essential for positive selection and the development of single-positive thymocytes. Highest levels of expression are found in CD4+CD8+ double-positive thymocytes, with lower expression found in mature T cells. In addition to Grb1, Themis has been found to associate with PLC gamma 1 and LAT and is quickly phosphorylated by SLP-76 following TCR signaling. There are 5 isoforms of mouse Themis that are produced as a result of alternative splicing.
Specifications
Specifications
| Antigen | Themis |
| Applications | ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | 7G7 |
| Concentration | 0.8 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | Themis |
| Gene Accession No. | Q8N1K5 |
| Gene Alias | bA325O24.3; bA325O24.4; C6orf190; C6orf207; E430004N04Rik; FLJ40584; Gasp; GRB2-associated protein; Grb2-associating protein; MGC163388; Protein THEMIS; Protein thylex; RGD1560849; signaling phosphoprotein specific for T cells; SPOT; THEMIS; thylex; thymocyte expressed molecule involved in selection; thymocyte selection associated; thymocyte selection pathway associated; thymocyte-expressed molecule involved in selection; Tsepa |
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