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Terfenadine, MedChemExpress

Product Code. 16408676
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Quantity:
100 mg
Unit Size:
100mg
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Product Code. 16408676

Brand: Medchem Express HYB1193

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Description

MedChemExpress Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.

Terfenadine ((±)-Terfenadine) is a potent open-channel blocker of hERG with an IC50 of 204 nM. Terfenadine, an H1 histamine receptor antagonist, acts as a potent apoptosis inducer in melanoma cells through modulation of Ca2+ homeostasis. Terfenadine induces ROS-dependent apoptosis, simultaneously activates Caspase-4, -2, -9.

Specifications

Chemical Name or Material Terfenadine
CAS 50679-08-8
Color White
Purity Grade Notes Research
Molecular Formula C32H41NO2
Quantity 100 mg
Synonym (±)-Terfenadine MDL-991
Solubility Information DMSO : ≥ 50 mg/mL (106.01 mM) ∣H2O : < 0.1 mg/mL (insoluble)
SMILES OC(C1=CC=C(C(C)(C)C)C=C1)CCCN2CCC(C(C3=CC=CC=C3)(O)C4=CC=CC=C4)CC2
Molecular Weight (g/mol) 471.67
Formula Weight 471.67
Percent Purity 99.86%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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