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SGC-iMLLT, MedChemExpress

Product Code. 16480997
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Product Code. 16480997 Supplier Medchem Express Supplier No. HY112804
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Estimated Shipment: 22-07-2026
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Description

MedChemExpress SGC-iMLLT is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC50 of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with Kds of 0.129 and 0.077 μM, respectively.

SGC-iMLLT is a first-in-class chemical probe and a potent, selective inhibitor of MLLT1/3-histone interactions with an IC50 of 0.26 μM. SGC-iMLLT shows high binding activity towards MLLT1 YEATS domain (YD) and MLLT3 YD (AF9/YEATS3) with Kds of 0.129 and 0.077 μM, respectively.

Specifications

Chemical Name or Material SGC-iMLLT
Physical Form Powder
CAS 2255338-25-9
Color White
Quantity 50 mg
Purity Grade Notes Research
Molecular Formula C22H24N6O
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 83.33 mg/mL (214.51 mM; Need ultrasonic)
SMILES CN1N=CC2=CC(C(NC3=CC=C(NC(CN4[C@@H](C)CCC4)=N5)C5=C3)=O)=CC=C21
Molecular Weight (g/mol) 388.47
Formula Weight 388.47
Percent Purity 95.0%
Grade Research
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Research purposes only

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