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Selpercatinib, MedChemExpress

Product Code. 16474818
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Product Code. 16474818 Supplier Medchem Express Supplier No. HY114370

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Description

MedChemExpress Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity.

Specifications

Chemical Name or Material Selpercatinib
CAS 2152628-33-4
Color White
Purity Grade Notes Research
Molecular Formula C29H31N7O3
Quantity 10 mg
Synonym LOXO-292
Solubility Information DMSO : 62.5 mg/mL (118.91 mM; Need ultrasonic)
SMILES N#CC1=C2C(C3=CC=C(N4CC(C5)N(CC6=CC=C(OC)N=C6)C5C4)N=C3)=CC(OCC(C)(O)C)=CN2N=C1
Molecular Weight (g/mol) 525.6
Formula Weight 525.6
Percent Purity 98.06%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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