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SAR405838, MedChemExpress

Product Code. p-200100082
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Product Code. 16470138 Supplier Medchem Express Supplier No. HY18986

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Description

MedChemExpress SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.

SAR405838 (MI-77301), an analog of MI-773, is a highly potent and selective MDM2-p53 interaction inhibitor. SAR405838 binds to MDM2 with a Ki of 0.88 nM. SAR405838 induces apoptosis and has potent antitumor activity.

Specifications

Chemical Name or Material SAR405838
CAS 1303607-60-4
Color Off-White
Purity Grade Notes Research
Molecular Formula C29H34Cl2FN3O3
Quantity 5 mg
Synonym MI-77301
Solubility Information DMSO : 100 mg/mL (177.78 mM; Need ultrasonic)
SMILES O=C([C@H](N[C@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2F)[C@@]31C(NC4=C3C=CC(Cl)=C4)=O)N[C@@H]5CC[C@@H](O)CC5
Molecular Weight (g/mol) 562.5
Formula Weight 562.5
Percent Purity 95.0%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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