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Rociletinib, MedChemExpress

Product Code. 16476896
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Product Code. 16476896 Supplier Medchem Express Supplier No. HY15729

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Description

MedChemExpress Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

Rociletinib (CO-1686) is an orally delivered kinase inhibitor that specifically targets the mutant forms of EGFR including T790M, and the Ki values for EGFRL858R/T790M and EGFRWT are 21.5 nM and 303.3 nM, respectively.

Specifications

Chemical Name or Material Rociletinib
CAS 1374640-70-6
Color Off-White
Purity Grade Notes Research
Molecular Formula C27H28F3N7O3
Quantity 100 mg
Synonym CO-1686 AVL-301 CNX-419
Solubility Information DMSO : ≥ 43 mg/mL (77.40 mM)
SMILES C=CC(NC1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C(C)=O)CC4)C=C3OC)=NC=C2C(F)(F)F)=C1)=O
Molecular Weight (g/mol) 555.55
Formula Weight 555.55
Percent Purity 98.12%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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