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RN486, MedChemExpress
Description
RN486 is a potent, selective and orally active Btk inhibitor with an IC50 of 4.0 nM and a Kd of 0.31 nM. RN486 is less active for other kinases. RN486 can be used for rheumatoid arthritis and systemic lupus erythematosus research.
Specifications
Specifications
| Chemical Name or Material | RN486 |
| CAS | 1242156-23-5 |
| Color | Light Yellow |
| Purity Grade Notes | Research |
| Molecular Formula | C35H35FN6O3 |
| Quantity | 10 mg |
| Solubility Information | DMSO : 24 mg/mL (39.56 mM; Need ultrasonic and warming) |
| SMILES | O=C1C(NC2=CC=C(N3CCN(C)CC3)C=N2)=CC(C4=CC=CC(N5C=CC(C=C(C6CC6)C=C7F)=C7C5=O)=C4CO)=CN1C |
| Molecular Weight (g/mol) | 606.69 |
| Formula Weight | 606.69 |
| Show More |
Research purposes only
Product Title
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