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Tocris Bioscience™ Reversan
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Product Code. 18044532
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Quantity:
10 mg
50 mg
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10mg
50mg
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Product Code. 18044532

missing translation for 'mfr': Tocris Bioscience™ 3722/10

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This item is not returnable. View return policy

Description

Selective MRP1 and P-gp inhibitor

Reversan is a selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin (Cat. No. 2252), vincristine (Cat. No. 1257) and etoposide (Cat. No. 1226) by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo. Does not sensitize MRP2, MRP3, MRP4 or MRP5 transporters to known substrates.
TRUSTED_SUSTAINABILITY

Specifications

Quantity 10 mg
Product Type Reversan
Purity 0.95
Molecular Weight (g/mol) 441.52
Inhibitors Reversan

For Research Use Only

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